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Genetic anomalies. Mutations in certain genes can lead to disorders that affect the sweat glands.
Anhidrosis can occur with many skin conditions, including psoriasis. Among these skin diseases are exfoliative dermatitis, which is characterized by severe flaking of the skin, prickly heat, scleroderma, which causes stiffness and tightness of the skin, as well as ichthyosis - very dry, flaky skin.
Thermoregulation disorders are associated with the most serious complications in anhidrosis. Children are especially vulnerable because their body temperature rises faster than that of adults and their body releases stored heat less efficiently. All children should be closely monitored for possible overheating, but extra precautions should be taken when a child has anhidrosis.
Thermoregulatory disorders associated with anhidrosis include
These muscle spasms, which can occur in the muscles of the legs, arms, abdomen, and back, are usually more painful and longer lasting than typical nocturnal leg cramps. Overheat. Symptoms such as weakness, nausea, and palpitations tend to start after exercise. Any person with heat stroke should be closely monitored, as symptoms can worsen quickly. This life-threatening condition occurs when body temperature reaches 40 C or higher. If this condition is not immediately treated, heat stroke can cause hallucinations, unconsciousness, coma, and even death.